Ocupres 0.5% Eye Drops 5ml

✔️ Uses of Ocupres 0.5% Eye Drops

Glaucoma, Ocular hypertension (high fluid pressure of eyes)

✔️ How does Ocupres 0.5% Eye Drops work?

It inhibits the binding of certain receptors (beta receptors) on the tissues lining the inner wall of the eyeball. These tissues increase the production of aqueous humor (fluid of the eye). So, by inhibiting beta receptors, there is a reduction in aqueous humor production, and therefore, pressure in the eyes is reduced. The exact mechanism of action is not established.

✔️ Side Effects of Ocupres 0.5% Eye Drops

• Redness, itching, stinging, or burning in the eyes
• Swelling of eyelid
• Dry eyes

✔️ Quick Suggestions:

• Timolol helps lower high pressure in the eye and reduces the risk of vision loss.
• Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
• Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
• Notify your doctor if you have lung or heart diseases as Timolol may worsen these conditions.
• A stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
• Make sure to use within 4 weeks of opening the bottle.

✔️ Indications:

Ocupres 0.5% Eye Drops is used to treat elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

✔️ Pharmacology

Timolol, the active ingredient, is a non-selective β-adrenergic receptor blocker. It reduces intraocular pressure by decreasing the formation of aqueous humor in the eye.

✔️ Dosage & Administration:

Adult Dose

For Open-Angle Glaucoma and Ocular Hypertension

• Initial Dose: One drop in the affected eye(s) twice a day.
• Maintenance Dose: Reduce to one drop per day if the condition is controlled.

Child Dose

• Safety and Efficacy: Not established for pediatric use.

Instructions for Use

• Ensure your hands are clean by washing them thoroughly before and after using Timolol.
• Find a comfortable position and tilt your head backward.
• Gently pull your lower eyelid downwards with your index finger to create a small pocket.
• Instil the number of drops as prescribed by your doctor into the pocket of the lower eyelid.
• Close your eyes for 1-2 minutes to allow the medication to be absorbed properly.
• Replace the outer cap of the bottle immediately after use.
• Do not let the tip of the container touch your eye, eyelids, or any other surface to avoid contamination.

✔️ Interaction

Timolol may interact with various medications, which can alter its effectiveness or increase the risk of side effects. Some notable interactions include:

High Blood Pressure-Lowering Medicines:

• Clonidine
• Reserpine
• Amlodipine
• Nifedipine
• Diltiazem
• Metoprolol
• Verapamil

Heart-Related Medicines:

• Digoxin

Antidepressants:

• Paroxetine
• Fluoxetine

Antimalarial Drugs:

• Quinidine

Medicines for Severe Allergic Reactions:

• Adrenaline

Drug-Food Interaction

• Marijuana:
  • Avoid intake of marijuana while taking Timolol. Marijuana can decrease the effect of Timolol and cause increased heart rate, high blood pressure, or other heart-related problems.

Drug-Disease Interactions

Inform your doctor if you have any of the following conditions before taking Timolol:

1. Diabetes: Timolol can mask the symptoms of low blood sugar.
2. Asthma or Chronic Obstructive Pulmonary Disease (COPD): Timolol may cause bronchospasm.
3. Heart Problems: Timolol can exacerbate heart failure and other heart conditions.
4. Raynaud's Disease or Raynaud's Syndrome: Timolol may worsen poor blood circulation.
5. Hyperthyroidism (Overactive Thyroid Gland): Timolol can mask symptoms of hyperthyroidism.

✔️ Contraindications

Ocupres 0.5% Eye Drops is contraindicated in patients with bronchial asthma, severe chronic obstructive pulmonary disease (COPD), sinus bradycardia, second or third-degree atrioventricular block, overt cardiac failure, cardiogenic shock, and hypersensitivity to any component of the product.

✔️ Pregnancy & Lactation

Ocupres 0.5% Eye Drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Since Timolol can be detected in breast milk, a decision should be made to either discontinue nursing or the medication based on the drug's importance to the mother.

✔️ Precautions & Warnings

Use with caution in patients with inadequate cardiac function, diabetes mellitus, myasthenia gravis, cerebrovascular insufficiency, or a history of atopy. Avoid abrupt withdrawal and monitor for signs of hyperthyroidism and hypoglycemia.

✔️ Storage:

Store between 15-30°C. Avoid freezing and protect from light. Keep out of reach of children.